I just rode through a lot of that area last week. Hotels were hard to get in some places. I only came acrossed one motel 6 in I think Idaho that was closed for covid reasons, otherwise a bunch of them were just full. Utah and Wyoming had occupant limits in gas stations and nearly every restaurant has carry out only or very limited seating. One exception was Las Vegas. In fact, Nevada had the least amount of restrictions from what I noticed. The stretch of Colorado I rode through, North to South was a bit smoky, but still a blast to ride through.
Like Liquidsilver, I was way off of interstates. It seems odd that 85-90 mph is a relaxing ride on back highways, but on the interstate traveling the same speed is more work. Turbulence from trucks and motorhomes make it unenjoyable I guess.